KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

PLoS One · 2022 · PMC8791453 · PMID 35081118

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failed to reach significanceno p-value reported

When the 14 late-stage SMGs were examined in the TCGA early-stage data, only Krüppel-like factor 3 ( KLF3 ) and Paired box 6 ( PAX6 ) failed to reach significance as early-stage SMGs, despite the inclusion of enough early-stage cases to ensure adequate statistical power.

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