highly significantP < 0.001
All SCAF fractions (except for SCAF4 (high ionic strength and between 10 and 100 kDa; P < 0.01)) elicited highly significant ( P < 0.001) lymphoproliferative responses at the highest concentration (100 μg/ml) with a mean 13.2% (+/− 1.4 SD) increase observed across treatments compared with the negative control (Fig. 2 A).