A Novel Prognostic Predictor of Immune Microenvironment and Therapeutic Response in Kidney Renal Clear Cell Carcinoma based on Necroptosis-related Gene Signature.

Int J Med Sci · 2022 · PMC8795799 · PMID 35165523

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highly significantno p-value reported

Mixed subgroup affiliation was associated with a highly significant shorter OS in KIRC 52 . mtDNA has been reported to release to the cytosol of cancer cells that bear necroptosis and ZBP1 senses the cytosolic mtDNA for the initiation of cancer necroptosis under glucose deprivation or stress condition 53 - 55 .

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