Taken together, the existing evidence suggests that there might not be significant correlation between IL - 6 gene 174G/C polymorphism and skin cancer. 597G/A is another SNP located in the promoter region of IL-6, which can regulate the immune response by regulating the level of IL-6 in vivo ( 16 ).
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Association between single nucleotide polymorphisms of IL-6 and susceptibility to skin cancer: a meta-analysis and systematic review.
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