Intergenerational effects of preconception opioids on glucose homeostasis and hepatic transcription in adult male rats.

For insulin (panel A), there was a significant main effect of adolescent exposure (F (1,18) = 12.6; p = 0.002), no main effect of diet (F (1,18) = 2.1; p = 0.15) and a marginally significant interaction (F (1,18) = 4.1; p = 0.05).

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