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Stratification of atopic dermatitis patients by patterns of response to proactive therapy with topical tacrolimus: low serum IgE levels and inadequately controlled disease activity at the start of treatment predict its failure.

Ann Med · 2021 · PMC8805968 · PMID 34797182

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an increasing trendno p-value reported
On the other hand, only the mean TARC level showed an increasing trend in the remission induction period of the proactive-dropout group, suggesting that some of the patients in this group had subclinical inflammation that had not been adequately controlled by TCS.

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