Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism.

Dis Model Mech · 2022 · PMC8807579 · PMID 34842276

Europe PMC DOI

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highly significantP =1.4×10 −9actually significant

Indeed, χ 2 tests for independence revealed that there is a highly significant dependence of APOE genotype and litter across the entire 3-month-old dataset (χ 2 =82.7, d.f.=20, P =1.4×10 −9 ), as well as within only male samples (χ 2 =43.1, d.f.=14, P =8.2×10 −5 ) and within only female samples (χ 2 =39.3, d.f.=14, P =3.0×10 −4 ).

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