Therapeutic Targets of Bufalin on Renal Carcinoma and Mechanisms: Experimental Validation of Network Pharmacology Analysis.

Evid Based Complement Alternat Med · 2022 · PMC8816594 · PMID 35126601

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extremely significantno p-value reported

This study also revealed that the number of cells in the G2/M phase increased as the bufalin concentration increased which is extremely significant, and when cycling cells face stress, they are arrested at one of the two cell cycle checkpoints, G2/M or G1/S.

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