BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.

Nat Cell Biol · 2022 · PMC8820466 · PMID 35027731

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Genes adjacent to Brd2-bound sites detected in our experiment showed a highly significant overlap with Brd2-bound sites previously mapped by ChIP-seq in NCI-H23 34 cells, another lung epithelium-derived cancer cell line ( Fig. 5a ).

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