Qing Zao Fang (QZF) Alleviates the Inflammatory Microenvironment of the Submandibular Gland in Sjögren's Syndrome Based on the PI3K/Akt/HIF-1<i>α</i>/VEGF Signaling Pathway.

In contrast to the control group, the average water intake of mice in the model group was significantly increased, and the water intake preferred an increasing trend with the development of the disease; compared with the SS model, mice in the high- and medium-dose QZF group and the hydroxychloroquine group indicate decreased average water intake at 16 weeks of age and the water intake showed a continuous decreasing trend as the course of the disease progressed ( Figure 1(a) ).

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