The one-way ANOVA showed no significant differences ( p > 0.05) in Pertuzumab light chain production across the seeding densities tested despite a decreasing trend above 6 × 10 5 cells/mL, where production at 10 × 10 5 cells/mL was only 41% (70 μg/mL) that of the control (177 μg/mL).
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Augmenting recombinant antibody production in HEK293E cells: optimizing transfection and culture parameters.
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