Notably, PYL recruitment led to a marginally significant decrease in H3Ac level in 16B-Y cells but the decrease was not statistically significant in 91B-Y cells ( Fig. 4D , P = 0.04 and P = 0.28 comparing the DMSO and ABA treatments in 16B-Y and 91B-Y cells, respectively, using an one-way ANOVA).
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Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing.
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