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A serum proteomic study of two case-control cohorts identifies novel biomarkers for bipolar disorder.

Transl Psychiatry · 2022 · PMC8826439 · PMID 35136035

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Several prior studies have associated bipolar disorder with altered concentrations of IL-1 receptor antagonist [ 18 , 35 , 43 , 44 ] and IL-6 [ 33 – 35 ], which in our results did not quite reach statistical significance in both cohorts when controlling for relevant covariates.

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