Among IDH-MUT tumors (Additional file 5 : Figure S5B), 2 of 3 datasets (TCGA and CGGA325) showed significant survival associations among these immune cell-based clusters, while the 3rd dataset (CGGA693) showed a statistical trend.
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Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology.
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