Again, akin to percentages, there was a considerably significant reduction in absolute numbers of macrophages, cDCs, and neutrophils in IL-4Rα -/- mice ( Figures 6E–H ).
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Interleukin-4 Responsive Dendritic Cells Are Dispensable to Host Resistance Against <i>Leishmania mexicana</i> Infection.
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Despite this comparable phenotype, surprisingly, IL-4 production in CD11c cre IL-4Rα -/lox mice was significantly increased with an increasing trend of IL-13 when compared to littermate controls.