We thus explored the role of significant factors in the above Cox and logistic regression multivariate analyses (radiotherapy and surgery against hypothalamic involvement) and found a highly significant effect of hypothalamic involvement (OR 6.1, 95% CI 1.7–21.7, p 0.005), as well as radiation (OR 16.2, 95%CI 1.7–158.6, p 0.017) and surgical intervention (OR 4.8 95% CI 1.3–17.2, p 0.015), to influence the onset of APD, with no factor prevailing on the others. 2.6.
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A 40-Year Cohort Study of Evolving Hypothalamic Dysfunction in Infants and Young Children (<3 years) with Optic Pathway Gliomas.
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