[ 55 ] (DAP-G) used a similar idea of avoiding the enumeration of all 2 n causal configurations by focusing only on non-negligible ones but used a deterministic method instead; their Deterministic Approximation of Posterior (DAP) algorithm restricts the search space based on two assumptions: (1) The true causal variants should have medium to highly significant association p -value.
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Methods for statistical fine-mapping and their applications to auto-immune diseases.
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