PTEN promoter methylation predicts 10-year prognosis in hormone receptor-positive early breast cancer patients who received adjuvant tamoxifen endocrine therapy.

Breast Cancer Res Treat · 2022 · PMC8841328 · PMID 34978016

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

borderline significanceP = 0.057so close (0.05 < p ≤ 0.1)

In TCGA validation cohort, there was also a trend of higher methylation of the − 796 CpG island correlating with shorter disease-free intervals, with borderline significance ( P = 0.057).

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