Schwann Cell-Derived Exosomes Induce the Differentiation of Human Adipose-Derived Stem Cells Into Schwann Cells.

Front Mol Biosci · 2021 · PMC8841477 · PMID 35174212

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Validation of PI3K-Akt Signaling Pathway According to the KEGG pathway analysis, the PI3K-Akt signaling pathway was highly significant and enriched with a large number of target genes ( Figure 5B ), thus suggesting that the PI3K-Akt signaling pathway may play an important role in the differentiation of ADSCs into Schwann cells induced by exosomes.

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