A Comparative Study of Acidosis in Diabetic Advanced Chronic Kidney Disease Patients on and off Metformin.

Cureus · 2022 · PMC8846262 · PMID 35186553

Europe PMC DOI

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highly significantp<0.001actually significant

Mean HbA1c of patients who were taking metformin was 7.8 ± 1.4 as compared to patients who were not using metformin (8.4 ± 1.5), and this difference is highly significant (p<0.001) Similarly, the patients who were using metformin had high values of bicarbonate as compared to non-users (23 ±3 and 19.7± 3.4, respectively), and this difference is highly significant in the two groups (p<0.001).

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