Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis.

Thorax · 2022 · PMC8847543 · PMID 34400514

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an increasing trendno p-value reported

Intriguingly, a retrospective analysis of recent single-cell RNA-seq datasets ( GSE135893 33 and GSE136831 37 ) revealed that although not statistically significant, an increasing trend of PDIA3 signature in association with ATII-epithelial and club cell signatures in patients with IPF ( online supplemental figure 7A, B ).

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