Clinically relevant preclinical animal models for testing novel cranio-maxillofacial bone 3D-printed biomaterials.

Study duration including time points and analysis strategy In the presented studies, the endpoint and time points appear to follow an overall trend, with typical endpoints ranging from 8–12 weeks, which resembles the typical bone healing process of 6–8 weeks (and in some cases, 12 weeks) in humans and also to make use of appropriate endpoints to validate the outcome.

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