A dominant tubulin mutation causes cerebellar neurodegeneration in a genetic model of tubulinopathy.

Sci Adv · 2022 · PMC8849301 · PMID 35171680

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highly significantno p-value reported

Quantification showed an increase in apoptotic cells at P21 in Tubb4a Jit/Jit mutants compared with WT and a highly significant increase at P35, consistent with the strong reduction of IGL size at that stage ( Fig. 2N ).

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