<i>Abcc6</i> Null Mice-a Model for Mineralization Disorder PXE Shows Vertebral Osteopenia Without Enhanced Intervertebral Disc Calcification With Aging.

Front Cell Dev Biol · 2022 · PMC8850990 · PMID 35186933

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a small trendno p-value reported

Staining for ARGxx, an ACAN neoepitope generated by ADAMTS-dependent degradation, showed a small trend of increase in the AF compartment of ABCC6 −/− mice at 7–8 months, whereas a significant decrease was noted at 16–18 months ( Figures 5A–A" ).

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