Barely Significant
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Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation.

Front Oncol · 2022 · PMC8851913 · PMID 35186762

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may be significantno p-value reported
Contrastingly, our data suggest a strong effect of MET + TMP on migration by significantly reducing wound closure, demonstrating that the sub-IC 50 concentrations of both drugs may be significant in preventing the metastasis of HCC.

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