Fine-mapping of intracranial aneurysm susceptibility based on a genome-wide association study.

Remaining 16 IA-predicting candidate loci (6 intergenic, 8 intronic, and 2 synonymous SNPs; log10BF > 6.1 and p < 5 × 10 –8 ) were not accompanied by any neighbor promotor or functional variations such as UTR, missense, and nonsense SNPs that showed both moderate to strong LD (0.5 < r 2 < 1) and marginally significant associations ( p < 0.0001, data not shown).

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