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Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men.

Emerg Microbes Infect · 2022 · PMC8855726 · PMID 35045788

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an increasing trendno p-value reported
On the contrary, there was an increasing trend in the susceptibility of S. flexneri to ampicillin and azithromycin and S. sonnei to trimethoprim-sulfamethoxazole (TMP-SMX) ( Table 3 ).

also in 63,971 other papers

a decreasing trendno p-value reported
The annual case number of newly diagnosed HIV infection continued to increase until 2018, when a decreasing trend was noted with implementation of programmes of HIV self-testing, pre-exposure prophylaxis, and rapid initiation of antiretroviral therapy within 7 days of confirmed HIV diagnosis.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.