Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models.

JCI Insight · 2022 · PMC8855813 · PMID 34847076

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a decreasing trendno p-value reported

The message levels of proinflammatory markers TNF-α, IL-6, IFN-γ, and IL-23 show a significant decrease with pirfenidone treatment, while IL-12α and NLRP3 show a decreasing trend ( Supplemental Figure 6 , G–L).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.