Although T RM increases at 8 weeks after aerosol vaccination, compared with the baseline, were only marginally statistically significant (95% CI) probably due to small sample sizes, remarkable proportions of Ag85A-specific CD4 T cells (~20%) and CD8 + T cells (~54%) present in the airways of aerosol vaccine groups were T RM ( Figure 4D ).
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Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans.
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