Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs.

Pharm Biol · 2022 · PMC8856114 · PMID 35171063

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an increasing trendno p-value reported

Results Bodyweight, food intake, and liver weight The body weights of the normal rats showed an increasing trend, while the body weights of rats decreased by approximately 20% following 8 weeks of MCD diet administration.

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