Renin-angiotensin system inhibitors combined with cisplatin exacerbate cisplatin-induced nephrotoxicity in mice.

Transl Oncol · 2022 · PMC8857575 · PMID 35182957

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an increasing trendno p-value reported

An increasing trend in CRE level was observed in the CDDP+Low ENA and CDDP+Low TEL groups compared to the CDDP group (day 7: 0.66 + 0.09 mg/dL, day 14: 0.68 + 0.04 mg/dL) on days 7 (CDDP+Low ENA: 0.84 + 0.17 mg/dL, CDDP+Low TEL: 1.07 + 0.15 mg/dL) and 14 (CDDP+Low ENA: 1.00 + 0.49 mg/dL, CDDP+Low TEL: 1.03 + 0.12 mg/dL).

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