The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer.

Oncotarget · 2022 · PMC8858079 · PMID 35198099

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highly significantno p-value reported

Although IGFBP-3 is the cardinal regulator of IGF-I activity and, by extension, has a highly significant impact on tumorigenesis, the other IGFBPs have important biological roles in the inhibition or potentiation of IGF, as well [ 29 – 31 ].

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