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Systemic delivery of tenofovir alafenamide using dissolving and implantable microneedle patches.

Mater Today Bio · 2022 · PMC8858997 · PMID 35243292

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a decreasing trendno p-value reported
The administration of MAPs led to pharmacokinetic profiles that started with a decreasing trend in TFV concentrations followed by significantly different plasmatic peaks (T max ) at 0.09 ​± ​0.07 and 0.82 ​± ​0.41 days for dissolving and implantable MAPs, respectively.

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