SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers.

Mol Cell · 2022 · PMC8860380 · PMID 35081363

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highly significantno p-value reported

For instance, it was highly significant in the liver and small intestine for dual domains while it was anticorrelated for all other H3K9me3 regions ( Figures S7 C and S7D), suggesting that only H3K9me3 is not sufficient to call dormant enhancers.

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