CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function.

Sci Rep · 2022 · PMC8863776 · PMID 35194103

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marginally significantno p-value reported

S -Mephenytoin N -demethylase activity appeared to be significantly influenced by g.15631C > T, and marginally significant impact of g.18053A > G was demonstrated; however, the haplotype g.-82 T/15631 T/18053G/25505 T ( CYP2B6*6 ) did not affect CYP2B6 activity at all.

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