The premorbid frailty index demonstrates a borderline significant association with the development of post-stroke delirium after adjustment for age, sex, and medication count. 14 Pre-stroke frailty is independently associated with poorer post-stroke cognition after adjustment for age, delirium, pre-stroke cognitive impairment, and stroke severity. 34 Pre-
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Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine.
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