COVID-19 infection and neurodegeneration: Computational evidence for interactions between the SARS-CoV-2 spike protein and monoamine oxidase enzymes.

Specifically, through the N501Y mutation, the SARS-CoV-2 increases the individual contribution of this residue by as much as –6.7 kcal mol −1 , which is both highly significant and highly disturbing, knowing that this mutation is well conserved and present in the UK and Brazilian strains as well [53] , although most likely independently evolved [55] .

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