IQSEC2 mutation associated with epilepsy, intellectual disability, and autism results in hyperexcitability of patient-derived neurons and deficient synaptic transmission.

Mol Psychiatry · 2021 · PMC8873005 · PMID 34535765

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0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

almost significantlyp = 0.055so close (0.05 < p ≤ 0.1)

The spike height was almost significantly larger in the IQSEC2 mutant neurons than in the controls (Fig. 1 i, 26.6 ± 6.1 mV) (control) vs. 37 ± 2.2 mV ( IQSEC2 mutant, p = 0.055).

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