Serotonin depletion impairs both Pavlovian and instrumental reversal learning in healthy humans.

Extent of depletion was not correlated with the magnitude of the SCR difference score in the acquisition phase ( r (27) = 0.210, p = 0.294); however, there was a highly significant correlation between greater depletion and a more pronounced reversal learning deficit ( r (27) = −0.536, p = 0.004), depicted in Fig. 5 .

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