2-Deoxy-d-glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation.

Therefore, although 2‐DG has low pharmacological specificity, effects other than its anti‐inflammatory properties may not be significant, considering that no serious adverse events were observed in a clinical study, 58 see the next paragraph) using a human dose equivalent to that used in mice in this study.

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