Transcriptome Sequencing Reveals Key Genes in Three Early Phases of Osteogenic, Adipogenic, and Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Rats.

Front Mol Biosci · 2021 · PMC8873985 · PMID 35223983

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a decreasing trendno p-value reported

Integrated analysis of differential gene expression at 3 h of osteogenesis indicated that the top 10 DEGs ( Ccna2 , Cdc20 , Il6 , Mad2l1 , Top2a , Kif11 , Mcm4 , Asf1b , Rrm1 , and Pa2g4 ) in the PPI network were the hub genes; only one gene ( Il6 ) showed a decreasing trend compared to the control group.

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