A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity.

Pharmaceuticals (Basel) · 2022 · PMC8874578 · PMID 35215369

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We sourced the newly assembled ‘ Pandemic Response Box’ , which contains 400 structurally diverse and well-curated compounds with activities against key pathogenic bacteria ( n = 201 entities), funguses ( n = 46) and viruses ( n = 153), including highly significant pathogens, such as the bacterium Staphylococcus aureus and the virus Influenza A.

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