Barely Significant
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Population Pharmacokinetics of Amikacin in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation.

Pharmaceutics · 2022 · PMC8879580 · PMID 35214022

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highly significantno p-value reported
In patients on V-A ECMO, highly significant changes in drug pharmacokinetics can occur by interactions with the ECMO support, drug characteristics, and patient characteristics.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.