Barely Significant
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HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources.

Nat Commun · 2022 · PMC8885657 · PMID 35228537

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highly significantno p-value reported
Although the collected data are highly significant, an odds ratio of 2.35 with a cohort including over 6,000 patients may seem quite modest.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.