borderline significancep = 0.04
In another study of 362 patients with COPD who underwent cardiac catheterization and a 6MWD test as part of evaluation for lung transplantation, the prevalence of PH (mPAP >25 mm Hg and pulmonary arterial occlusion pressure <16 mm Hg) was 23% and 6MWD declined by 11 m for every 5 mm Hg rise in mPAP, but with borderline significance ( p = 0.04) ( 27 ).