U-shaped association of uric acid to overall-cause mortality and its impact on clinical management of hyperuricemia.

Redox Biol · 2022 · PMC8889273 · PMID 35228125

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highly significantno p-value reported

This may be of great significance for the development of hypertension since genome-wide association studies (GWAS) have identified the eNOS down-regulating SNP rs3918226 as a highly significant (p = 2.58.10 −13 ) risk factor for the development of hypertension( 145 ).

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