Semi-quantitative analysis of vascularization and new bone formation showed that blood vessel number and new bone area presented an increasing trend from the B-GH-DBM group and B-DGH-DBM group to the BRU-DBM group ( Fig. 6 D–F), implying that adding both DBM and VEGF in microgels promoted vascularization and bone regeneration.
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Large-sized bone defect repair by combining a decalcified bone matrix framework and bone regeneration units based on photo-crosslinkable osteogenic microgels.
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