A Dynamic Mass Redistribution Assay for the Human Sweet Taste Receptor Uncovers G-Protein Dependent Biased Ligands.

Front Pharmacol · 2022 · PMC8893300 · PMID 35250580

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barely significantno p-value reported

Accordingly, these agonists did not exhibit significant changes in their relative potency to that of sucralose [pEC 50 R(sucralose) values] between the two assays and only two of these agonists, alitame and acesulfame K, exhibited small and barely significant bias following analysis with the operational model.

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