Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies.

Front Pharmacol · 2022 · PMC8894812 · PMID 35250581

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A recent meta-analysis showed that individuals with CYP2C9 poor metabolizers were associated with significantly increased risk of NSAID-related gastrointestinal bleeding (OR: 1.90, p = 0.003) and indicated that CYP2C9*2 was a poor risk predictor, while CYP2C9*3 was a highly significant predictor of GI bleeding ( Macías et al., 2020 ).

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