Identifying cancer pathway dysregulations using differential causal effects.

Bioinformatics · 2022 · PMC8896597 · PMID 34927666

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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highly significantP -value < 10 − 20actually significant

Most notably, we observe a highly significant dysregulation of WNT11 →FZD1, WNT11 →FZD3 and WNT11 →FZD7 in stage II ( P -value < 10 − 20 ), as well as of WNT11 →FZD7 in stages I and II.

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